On immune cells, Toll-like receptors are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, or TLRs for short. But what signals activate TLRs, ...

Establishment of the Immunotoxicity AOP Framework: The binding of PCP to TLR5 was identified as the molecular initiating event. This event triggers a series of key events, activation of the TLR ...