Case Western Reserve University biomedical researchers develop first open-source, quality-control review tool for fast-growing digital pathology field There’s a low-tech problem troubling the ...

Tissue optical clearing is a fundamental technique that enhances light penetration deep into biological samples by reducing light scattering through refractive index homogenization. This process ...

It is now possible to obtain three-dimensional, high-resolution images of enzyme activity in tissue samples or whole organs -- thanks to probe molecules that anchor fluorescent dyes within tissue as ...

Steps for deep-tissue 3D-imaging. Embryos or neonates fixed with 4% PFA were optically cleared with 60% TDE or tissue-clearing reagent CUBIC-L/R, and imaged using stereoscopic, confocal, or two-photon ...

More than 40% of women have dense breast tissue. Here’s why mammography falls short—and how dense breast imaging is reshaping ...

Optical clearing, whereby biological tissues are rendered transparent to visible light, is a valuable route to imaging of cells and organs in their complete environment. Multiple variations of ...

Endoscopic optical coherence tomography is widely used to visualize tissue microstructures in real time, but current probes face clear limitations. Conventional designs struggle in narrow lumens, ...

Magnetic resonance imaging (MRI) is a well-reputed imaging modality for clinically managing patients who suffer from neurological disorders. It enables the discovery of macro- and microstructural ...

Researchers at Niigata University have used advanced three-dimensional (3D) imaging to reveal how amyloid β (Aβ) deposits spread along blood vessels in the human brain in cerebral amyloid angiopathy ...