DNA lesions are repaired by a cut-and-remove process called nucleotide excision repair. An in vitro biochemically defined system has been developed in which six repair factors are sufficient to excise ...

A gene that helped bowheads adapt to frigid Arctic waters also granted them extraordinary longevity. Could it help aging ...

Researchers found that losing a second protein, FIGNL1, allows cancer cells missing BRCA2 to restore DNA repair by reloading ...

Bowhead whales can live over 200 years thanks to a protein that helps their cells repair DNA damage efficiently.

An elegant collaboration between researchers in the UK's two core-funded Medical Research Council Research Institutes, the Laboratory of Medical Sciences (LMS) in London and the Laboratory of ...

Researchers have revealed the structural mechanisms of a major DNA repair pathway in human cells. The research, published today as a Reviewed Preprint in eLife, is described by the editors as a ...

A new study of the bizarre naked mole rat shows that the animals have evolved a DNA repair mechanism that could explain their longevity. These burrow-dwelling rats have a maximum life span of nearly ...

A study reveals the secrets behind the rodent’s remarkable ability to live 10 times longer than expected, without cancer or ...

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...

A new discovery offers hope for Huntington’s disease. This discovery provides hope that a DNA repair process may help slow or stop disease progression. Research has identified a critical DNA repair ...

This came up in a front page discussion recently, and I promised I'd do a bit of a brain dump. The motivation: people often talk about whether we're regulating the risks posed by exposure to radiation ...