DNA lesions are repaired by a cut-and-remove process called nucleotide excision repair. An in vitro biochemically defined system has been developed in which six repair factors are sufficient to excise ...

Researchers found that losing a second protein, FIGNL1, allows cancer cells missing BRCA2 to restore DNA repair by reloading ...

Researchers have revealed the structural mechanisms of a major DNA repair pathway in human cells. The research, published today as a Reviewed Preprint in eLife, is described by the editors as a ...

An elegant collaboration between researchers in the UK's two core-funded Medical Research Council Research Institutes, the Laboratory of Medical Sciences (LMS) in London and the Laboratory of ...

Bowhead whales can live over 200 years thanks to a protein that helps their cells repair DNA damage efficiently.

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...

Ageing is inevitable but the rate of decline can be offset by regular exercise, says Dr Paul Taylor, author of 'The Hardiness Effect' ...

A new discovery offers hope for Huntington’s disease. This discovery provides hope that a DNA repair process may help slow or stop disease progression. Research has identified a critical DNA repair ...

Naked mole-rats seem to have found nature’s cheat code for longevity. Scientists discovered that small tweaks in one of their proteins make it better at fixing DNA damage, helping the animals resist ...

This came up in a front page discussion recently, and I promised I'd do a bit of a brain dump. The motivation: people often talk about whether we're regulating the risks posed by exposure to radiation ...