CHICAGO (CBS) -- Lysosomes – membrane-bound structures within each cell of humans and all animals – are sometimes known as the cells' "garbage disposals" or "cellular janitors." The structures are ...

Metabolism guides the activation states of regulatory T cells, the immune cells that prevent inappropriate activation of the ...

Ishikawa, Japan - The correct functioning of our cells rests upon the precise orchestration of many complex processes and organelles. Lysosomes—vital cell organelles—are enzyme-filled subunits found ...

In a rare disease called mucolipidosis type II, people's hearts and abdomens swell, and their bones grow malformed. A lysosomal storage disorder, mucolipidosis type II causes edema of the internal ...

Today in Nature, University of Pittsburgh researchers describe for the first time a pathway by which cells repair damaged lysosomes, structures that contribute to longevity by recycling cellular trash ...

Researchers at the National Institutes of Health (NIH) have discovered a biological pathway that the novel coronavirus appears to use to hijack and exit cells as it spreads through the body. A better ...

Lysosomes are tiny sacs of digestive enzymes that declutter cells by breaking down waste. But they can also be troublesome: When their outer surface is damaged, their destructive proteins begin to ...

In many neurodegenerative disorders, microglia come down with a kind of indigestion, and no longer degrade lipids and other molecules. In the December 1 Science Translational Medicine, researchers led ...

C-terminal fragments of amyloid precursor protein have been blamed for endolysosomal dysfunction in Alzheimer’s disease. Now, scientists led by Wim Annaert at KU Leuven, Belgium, claim that’s because ...