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  1. Circulating free DNA - Wikipedia

    The term cfDNA can be used to describe various forms of DNA freely circulating in body fluids, including circulating tumor DNA (ctDNA), cell-free mitochondrial DNA (ccf mtDNA), cell-free …

  2. What is cell-free DNA? - Natera

    Cell-free DNA, or cfDNA, are fragments of DNA found circulating in the bloodstream. Doctors can use cfDNA to help inform medical plans for many conditions, including pregnancy, cancer, and …

  3. What is cell-free DNA? cfDNA Definition and Applications | QIAGEN

    What is cell-free DNA? Learn about cfDNA, circulating in blood at 120–220 base pairs, revolutionizing early disease detection and diagnostics.

  4. Cell-free DNA as a potential alternative to genomic DNA in …

    Sep 9, 2025 · Cell-free DNA (cfDNA) refers to fragmented DNA released into various body fluids such as blood plasma, urine, and cerebrospinal fluid [16]. The sources of cfDNA are diverse …

  5. Cell-Free DNA (cfdna): Definition, Differentiation, and Significance

    Cell-free DNA (cfDNA), a fragmented DNA present in the human bloodstream in a cell-free state, predominantly arises from processes of cellular necrosis and apoptosis.

  6. Cell-free DNA fragmentomics in cancer

    Oct 2, 2025 · The analysis of cell-free DNA (cfDNA) fragmentation patterns, known as “fragmentomics,” has opened new opportunities in noninvasive cancer diagnostics. Due to its …

  7. The Basics and Applications of Cell-Free DNA | The Scientist

    Nov 8, 2023 · Found circulating in peripheral blood, scientists use cell-free DNA (cfDNA) to assess genetic abnormalities, infections, cancer, transplant rejection, and cardiovascular disease.

  8. A hitchhiker’s guide to cell-free DNA biology - PMC

    Liquid biopsy provides a noninvasive window to the cancer genome and physiology. In particular, cell-free DNA (cfDNA) is a versatile analyte for guiding treatment, monitoring treatment …

  9. Cell Free DNA - an overview | ScienceDirect Topics

    Cell free DNA (cfDNA) are nucleic acid fragments that circulate in plasma, serum and other bodily fluids outside of cells, first discovered in 1948 by Mandel and Metais [1]. Cell free DNA is …

  10. cfDNA: mechanisms, applications and analysis | INTEGRA

    Jul 8, 2024 · Cell-free DNA (cfDNA) holds a wealth of information about our health, and has become a significant focus of biomedical research and screening due to its applications in …